Services

iBG-izmir core services have a strong infrastructure that provides a large spectrum of current technology based equipment for both academia and industry. Current status and laboratory capabilities of each core service are listed below.

Table 1. Current situation of iBG-izmir Core Facilities
Core Facility
Director Effective Date
Flow cytometer and Cell Sorting Laboratory Gerhard Wingender 2014 (Active)
Vivarium (Experimental Animals Unit) Umur Keleş 2015 (Active)
General Device Operating Unit
Bilge Kılıç 2016 (Active)
Histopathology Core Facility Ayça Danyeli 2016 (Active)
Electron Microscopic Imaging Laboratory Alper Bağrıyanık 2016 (Active)
Optical Imaging Core Facility
Serhat Tozburun 2016 (Active)
Genomics and Bioinformatics Yavuz Oktay 2016 (Active)
Open Lab. Bilge Kılıç 2017

Flow Cytometer and Cell Sorting Laboratory
The Flow Cytometry Core Facility of IBG is equipped with two of the most well-used flow cytometers currently. Only FDA approved cytometer Canto II  and FACSAria III are manufactured by Becton Dickinson Immunocytometry. Canto II – the 4-2-2 configuration we have can collect four fluorescence signals from a blue laser source, two fluorescence signals from a red laser source, and two fluorescence signals from a violet laser source. FACSAria III is a high-speed cell sorter flow cytometer which is equipped with 8 color, 3 laser system, and optional 4-way sorting.

Vivarium (Experimental Animals Unit)
iBG’s experimental animals unit is authorized by the Turkish Ministry of Food, Agriculture, and Livestock to produce mouse and zebrafish models for biomedical research. iBG-Vivarium aims to provide researchers the tools to generate animal models in basic and translational research in areas including, regenerative medicine, cancer, drug screening, metabolism diseases and artificial organ development. With its modern infrastructure, large holding capacity and experienced team, the iBG-Vivarium is a candidate to become a prominent experimental animal research facility in Turkey and Euro-Asia.

General Device Operating Unit
iBG General Device Operating Unit offers researchers of other institutions as well as the institute of our devices and equipment. Furthermore, it aims to provide service to life sciences researchers to utilize these devices, perform measurement and contribute to national and international projects.

Histopathology Core Facility
Histopathology core facility, with a manager (Pathologist MD) and two staff (a Pathologist, MD, and a histo-technician); gives tissue processing, embedding, sectioning, cytologic specimen preparation, histochemical, immunohistochemical and immunofluorescent staining services for the researchers using human or animal tissue.

Electron Microscopic Imaging Laboratory
Electron Microscopy Imaging Laboratory comprises electron microscope (SEM – STEM, EDX) and sample preparation system (critical point drying and gold plated) as well as correlative microscopy system. It will be operational from the second quarter of 2016.

Optical Imaging Core Facility
The Optical Imaging Core Facility provides affordable training for new users of any level of microscopy experience and access to modern optical microscopy and imaging for individuals in the fields of basic science research and clinical medicine. The facility has a variety of optical microscopy modalities including a fully motorized inverted fluorescent microscope for live cell imaging, a semi-motorized upright fluorescence microscope, a stereomicroscope for oblique and bright-field illumination, centering free phase contrast inverted microscopes, a fully motorized wide-angle upright microscope equipped with a high-resolution digital camera and fluorescence attachments, conventional bright-field upright microscopes, an inverted phase contrast/fluorescence microscope equipped with a high-resolution digital camera, and a confocal laser-scanning microscope. The facility will become fully operational tentatively in the second quarter of 2016.

Genomics and Bioinformatics
Within the Genomics and Bioinformatics, the following services are provided: DNA/RNA isolation from various sources of tissue and samples, PCR, PCR purification, qPCR, and DNA subcloning. Standard and advanced bioinformatic analysis of Next Generation Sequencing (NGS), as well as other types of genomic data services,  will be available to researchers and clinicians starting from June 2016. Whole exome, targeted sequencing (gene panels), RNA-seq, and other advanced NGS services will be provided after December 2016.

Open Lab.
Open Lab. provides one or more rented benches and cell culture to people or institutions.